CMap Candidate Details
Structure:
| CMap ID: | C01990 |
| Pert ID: | BRD-K36270037 |
| Compound Name: | esculin |
| Targets: | |
| MoA: | antioxidant |
| SMILES: | OC[C@H]1O[C@@H](Oc2cc3ccc(=O)oc3cc2O)[C@@H](O)[C@@H](O)[C@@H]1O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121791 | BRD-K36270037 | HT29 | 3.33 uM | 24 h | 0.26 | 1.06 | 0.19 | 0.0 | 0.0 | 0.0 |
| 129753 | BRD-K36270037 | A375 | 0.03 uM | 24 h | -0.21 | -0.86 | 0.01 | 0.0 | 0.0 | 0.0 |
| 129787 | BRD-K36270037 | HA1E | 0.03 uM | 24 h | -0.28 | -1.15 | 0.44 | -0.32 | -1.07 | 0.78 |
| 129821 | BRD-K36270037 | HEK293 | 2.22 uM | 24 h | 0.27 | 1.11 | 0.26 | -0.3 | -1.02 | 0.61 |
| 129870 | BRD-K36270037 | HELA | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129948 | BRD-K36270037 | MCF10A | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.18 | 0.64 | 0.0 |
| 129995 | BRD-K36270037 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130032 | BRD-K36270037 | MDAMB231 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.99 | 0.39 |
| 130079 | BRD-K36270037 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.11 | 0.74 |
| 130104 | BRD-K36270037 | THP1 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 130152 | BRD-K36270037 | YAPC | 0.03 uM | 24 h | 0.3 | 1.25 | 0.53 | 0.35 | 1.23 | 1.19 |