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CMap Candidate Details

Structure:
CMap ID: C02004
Pert ID: BRD-K17016787
Compound Name: estriol
Targets: ESR1|ESR2
MoA: estrogen receptor agonist
SMILES: C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2761 BRD-K17016787 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42318 BRD-K17016787 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43509 BRD-K17016787 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43808 BRD-K17016787 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44085 BRD-K17016787 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91281 BRD-K17016787 HUH7 12 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
100155 BRD-K17016787 U2OS 6.66 uM 6 h -0.24 -1.0 0.15 0.0 0.0 0.0
119393 BRD-K17016787 A375 10 uM 24 h -0.29 -1.21 0.59 0.0 0.0 0.0
119425 BRD-K17016787 A549 1.11 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
119455 BRD-K17016787 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119491 BRD-K17016787 HCC515 0.37 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
119528 BRD-K17016787 HEPG2 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119561 BRD-K17016787 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119592 BRD-K17016787 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119624 BRD-K17016787 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).