CMap Candidate Details
Structure:
| CMap ID: | C02025 |
| Pert ID: | BRD-K48195008 |
| Compound Name: | ethinyl-estradiol |
| Targets: | ESR1|ESR2|NR1I2 |
| MoA: | estrogen receptor agonist; estrogenic hormone |
| SMILES: | C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@]2(O)C#C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24445 | BRD-K48195008 | A375 | 10 uM | 6 h | -0.21 | -0.89 | 0.03 | -0.32 | -1.07 | 0.78 |
| 24674 | BRD-K48195008 | A549 | 10 uM | 6 h | 0.19 | 0.78 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24781 | BRD-K48195008 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24913 | BRD-K48195008 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25027 | BRD-K48195008 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25165 | BRD-K48195008 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.02 | 0.61 |
| 25515 | BRD-K48195008 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |