CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02046
Pert ID:	BRD-K68232413
Compound Name:	etizolam
Targets:	GABRA1
MoA:	benzodiazepine receptor agonist
SMILES:	CCc1cc2c(s1)-n1c(C)nnc1CN=C2c1ccccc1Cl
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
97126	BRD-K68232413	A375	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126370	BRD-K68232413	A549	10 uM	24 h	0.21	0.86	0.01	0.0	0.0	0.0
126420	BRD-K68232413	HEK293	10 uM	24 h	0.23	0.94	0.06	0.0	0.0	0.0
126512	BRD-K68232413	MCF10A	1.11 uM	24 h	0.0	0.0	0.0	0.25	0.87	0.17
126548	BRD-K68232413	MDAMB231	10 uM	24 h	0.21	0.88	0.01	0.33	1.15	0.9
126592	BRD-K68232413	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134390	BRD-K68232413	HA1E	0.01 uM	24 h	-0.25	-1.04	0.21	0.25	0.9	0.21
134420	BRD-K68232413	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.32	1.13	0.82
134450	BRD-K68232413	HT29	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134487	BRD-K68232413	HUVEC	0.74 uM	24 h	0.0	0.0	0.0	0.28	0.99	0.39
134560	BRD-K68232413	MCF??7.00	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134617	BRD-K68232413	PC3	0.25 uM	24 h	0.25	1.05	0.17	0.34	1.21	1.15

Summary