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CMap Candidate Details

Structure:
CMap ID: C02047
Pert ID: BRD-A74667430
Compound Name: etodolac
Targets: PTGS1|PTGS2|RXRA
MoA: cyclooxygenase inhibitor
SMILES: CCc1cccc2c3CCOC(CC)(CC(O)=O)c3[nH]c12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5549 BRD-A74667430 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6488 BRD-A74667430 VCAP 10 uM 6 h 0.25 1.05 0.16 0.0 0.0 0.0
39408 BRD-A74667430 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39589 BRD-A74667430 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40713 BRD-A74667430 NEU 10 uM 24 h -0.28 -1.16 0.48 -0.35 -1.17 1.14
41013 BRD-A74667430 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41336 BRD-A74667430 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52760 BRD-A74667430 HEPG2 1.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53062 BRD-A74667430 MCF10A 100 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
127359 BRD-A74667430 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127433 BRD-A74667430 HA1E 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.23
127525 BRD-A74667430 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.85
127615 BRD-A74667430 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127651 BRD-A74667430 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127695 BRD-A74667430 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135373 BRD-A74667430 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.18 0.63 0.0
135411 BRD-A74667430 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135476 BRD-A74667430 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).