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CMap Candidate Details

Structure:
CMap ID: C02051
Pert ID: BRD-K49840922
Compound Name: etofylline-clofibrate
Targets: PPARA
MoA: platelet aggregation inhibitor
SMILES: Cn1c2ncn(CCOC(=O)C(C)(C)Oc3ccc(Cl)cc3)c2c(=O)n(C)c1=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125246 BRD-K49840922 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125334 BRD-K49840922 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125423 BRD-K49840922 MCF10A 10 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
125461 BRD-K49840922 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
125503 BRD-K49840922 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133373 BRD-K49840922 A549 0.25 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
133402 BRD-K49840922 HA1E 0.74 uM 24 h 0.26 1.1 0.24 0.24 0.85 0.14
133437 BRD-K49840922 HELA 0.01 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
133465 BRD-K49840922 HT29 0.01 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
133493 BRD-K49840922 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133568 BRD-K49840922 MDAMB231 0.25 uM 24 h 0.27 1.14 0.31 0.0 0.0 0.0
133614 BRD-K49840922 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
133645 BRD-K49840922 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).