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CMap Candidate Details

Structure:
CMap ID: C02053
Pert ID: BRD-K32405725
Compound Name: etomoxir
Targets: CPT1A
MoA: carnitine palmitoyltransferase inhibitor
SMILES: CCOC(=O)[C@@]1(CCCCCCOc2ccc(Cl)cc2)CO1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8934 BRD-K32405725 A375 90 uM 24 h 0.25 1.03 0.13 0.33 1.15 0.89
9198 BRD-K32405725 A549 90 uM 6 h 0.0 0.0 0.0 -0.39 -1.3 1.67
9716 BRD-K32405725 H1299 90 uM 6 h 0.0 0.0 0.0 0.19 0.69 0.01
10132 BRD-K32405725 HCC515 90 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10503 BRD-K32405725 HCT116 90 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10775 BRD-K32405725 HEPG2 90 uM 6 h 0.0 0.0 0.0 -0.37 -1.24 1.3
10968 BRD-K32405725 HT29 90 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11144 BRD-K32405725 MCF??7.00 90 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11750 BRD-K32405725 NCIH508 90 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.6
12034 BRD-K32405725 NCIH596 90 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12777 BRD-K32405725 SW480 90 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13467 BRD-K32405725 VCAP 90 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120705 BRD-K32405725 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120776 BRD-K32405725 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120811 BRD-K32405725 YAPC 0.04 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.54
129004 BRD-K32405725 HA1E 2.22 uM 24 h 0.28 1.16 0.36 0.0 0.0 0.0
129033 BRD-K32405725 HELA 0.25 uM 3 h -0.29 -1.21 0.59 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).