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CMap Candidate Details

Structure:
CMap ID: C02072
Pert ID: BRD-K13514097
Compound Name: everolimus
Targets: MTOR
MoA: mTOR inhibitor
SMILES: CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1OCCO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
649 BRD-K13514097 KMS34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
795 BRD-K13514097 OCILY19 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
818 BRD-K13514097 OCILY3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33679 BRD-K13514097 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33780 BRD-K13514097 A549 10 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
34047 BRD-K13514097 ASC 10 uM 24 h 0.23 0.98 0.09 0.0 0.0 0.0
34317 BRD-K13514097 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.91
34563 BRD-K13514097 HCC515 10 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.72
34832 BRD-K13514097 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35098 BRD-K13514097 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35297 BRD-K13514097 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35734 BRD-K13514097 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35935 BRD-K13514097 PC3 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
36501 BRD-K13514097 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36948 BRD-K13514097 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.18 1.15
87290 BRD-K13514097 BJAB 2.5 uM 24 h 0.29 1.23 0.49 0.0 0.0 0.0
87368 BRD-K13514097 HBL1 0.66 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
87418 BRD-K13514097 K562 0.66 uM 24 h 0.16 0.66 0.0 0.0 0.0 0.0
87507 BRD-K13514097 MINO 2.5 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
87570 BRD-K13514097 NALM6 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87620 BRD-K13514097 OCILY10 2.5 uM 24 h 0.27 1.13 0.29 0.0 0.0 0.0
87769 BRD-K13514097 SKMEL5 2.5 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
87792 BRD-K13514097 THP1 0.66 uM 24 h -0.18 -0.77 0.0 -0.25 -0.86 0.21
87854 BRD-K13514097 TMD8 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
95908 BRD-K13514097 YAPC 0.12 uM 6 h 0.0 0.0 0.0 0.23 0.81 0.09
96022 BRD-K13514097 PHH 3.33 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).