CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02073
Pert ID:	BRD-A68631409
Compound Name:	evodiamine
Targets:	TRPV1
MoA:	ATPase inhibitor; TRPV agonist
SMILES:	CN1C2N(CCc3c2[nH]c2ccccc32)C(=O)c2ccccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
8883	BRD-A68631409	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
9302	BRD-A68631409	AGS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
9608	BRD-A68631409	H1299	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
9912	BRD-A68631409	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
10290	BRD-A68631409	HCC515	10 uM	6 h	0.23	0.96	0.07	0.32	1.12	0.77
10413	BRD-A68631409	HCT116	10 uM	6 h	0.0	0.0	0.0	-0.23	-0.77	0.08
10682	BRD-A68631409	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
10914	BRD-A68631409	HT29	10 uM	24 h	-0.24	-1.01	0.16	0.0	0.0	0.0
11165	BRD-A68631409	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
11356	BRD-A68631409	NCIH2073	10 uM	6 h	0.26	1.09	0.22	0.22	0.78	0.07
11928	BRD-A68631409	NCIH596	10 uM	6 h	0.0	0.0	0.0	0.32	1.14	0.86
12479	BRD-A68631409	PC3	10 uM	24 h	0.0	0.0	0.0	0.32	1.13	0.83
13427	BRD-A68631409	VCAP	10 uM	24 h	0.0	0.0	0.0	0.3	1.08	0.65
96090	BRD-A68631409	A549	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.47

Summary