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CMap Candidate Details

Structure:
CMap ID: C02081
Pert ID: BRD-K33425534
Compound Name: exemestane
Targets: CYP19A1
MoA: aromatase inhibitor
SMILES: C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25358 BRD-K33425534 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117352 BRD-K33425534 A375 10 uM 24 h 0.25 1.04 0.15 0.24 0.84 0.13
117390 BRD-K33425534 A549 1.11 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.58
117432 BRD-K33425534 HA1E 10 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
117476 BRD-K33425534 HCC515 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
117523 BRD-K33425534 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117567 BRD-K33425534 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117605 BRD-K33425534 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117641 BRD-K33425534 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).