CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02083
Pert ID:	BRD-K81795818
Compound Name:	exherin
Targets:	CDH2
MoA:	cadherin antagonist
SMILES:	CC(C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(N)=O)NC(C)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125578	BRD-K81795818	A375	10 uM	24 h	-0.29	-1.19	0.53	-0.31	-1.04	0.66
125648	BRD-K81795818	HEK293	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125695	BRD-K81795818	HT29	3.33 uM	24 h	-0.24	-1.02	0.17	0.0	0.0	0.0
125729	BRD-K81795818	HUVEC	0.04 uM	24 h	-0.26	-1.07	0.27	0.0	0.0	0.0
125775	BRD-K81795818	JURKAT	3.33 uM	24 h	-0.37	-1.55	1.43	0.0	0.0	0.0
125825	BRD-K81795818	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125928	BRD-K81795818	YAPC	0.125 uM	24 h	0.0	0.0	0.0	-0.44	-1.48	15.35
133664	BRD-K81795818	A549	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133695	BRD-K81795818	HA1E	2.22 uM	24 h	0.0	0.0	0.0	-0.4	-1.34	1.85
133761	BRD-K81795818	HELA	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133853	BRD-K81795818	MCF10A	0.74 uM	24 h	-0.26	-1.07	0.28	0.0	0.0	0.0
133911	BRD-K81795818	MDAMB231	0.03 uM	24 h	-0.25	-1.04	0.22	0.0	0.0	0.0
133941	BRD-K81795818	PC3	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133975	BRD-K81795818	THP1	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary