CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02097
Pert ID:	BRD-K00673382
Compound Name:	famotidine
Targets:	HRH2
MoA:	histamine receptor antagonist
SMILES:	NC(N)=Nc1nc(CSCC\C(N)=N/S(N)(=O)=O)cs1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
25316	BRD-K00673382	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
51293	BRD-K00673382	MCF??7.00	10 uM	6 h	-0.18	-0.76	0.0	0.0	0.0	0.0
91054	BRD-K00673382	HUH7	10 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
99950	BRD-K00673382	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
122883	BRD-K00673382	HEK293	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122964	BRD-K00673382	HT29	10 uM	24 h	0.0	0.0	0.0	0.28	0.98	0.37
123008	BRD-K00673382	JURKAT	1.11 uM	24 h	-0.22	-0.91	0.05	-0.22	-0.75	0.07
123056	BRD-K00673382	MCF10A	0.04 uM	24 h	-0.23	-0.94	0.08	0.0	0.0	0.0
123097	BRD-K00673382	MDAMB231	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123143	BRD-K00673382	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.23	0.8	0.08
123169	BRD-K00673382	THP1	0.04 uM	24 h	-0.34	-1.42	1.42	-0.29	-0.99	0.5
131202	BRD-K00673382	A375	0.74 uM	24 h	-0.27	-1.14	0.42	0.0	0.0	0.0
131234	BRD-K00673382	A549	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131273	BRD-K00673382	HA1E	0.74 uM	24 h	0.31	1.3	0.73	0.0	0.0	0.0
131299	BRD-K00673382	HELA	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131345	BRD-K00673382	HUVEC	0.03 uM	24 h	0.0	0.0	0.0	0.32	1.13	0.82
131486	BRD-K00673382	YAPC	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary