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CMap Candidate Details

Structure:
CMap ID: C02102
Pert ID: BRD-A49622760
Compound Name: faropenem
Targets:
MoA: lactamase inhibitor
SMILES: CC(O)C1C2SC(C3CCCO3)=C(N2C1=O)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125243 BRD-A49622760 A375 1.11 uM 24 h -0.25 -1.06 0.26 -0.29 -0.96 0.44
125329 BRD-A49622760 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125421 BRD-A49622760 MCF10A 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
125456 BRD-A49622760 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
125553 BRD-A49622760 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133369 BRD-A49622760 A549 0.25 uM 24 h 0.0 0.0 0.0 0.24 0.87 0.17
133397 BRD-A49622760 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133432 BRD-A49622760 HELA 0.74 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
133462 BRD-A49622760 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133489 BRD-A49622760 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133564 BRD-A49622760 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
133589 BRD-A49622760 PC3 0.03 uM 24 h -0.27 -1.13 0.41 0.0 0.0 0.0
133610 BRD-A49622760 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).