CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02109
Pert ID:	BRD-K99107520
Compound Name:	felbamate
Targets:	GRIN1\|GRIN2A\|GRIN2B\|GRIN2C\|GRIN2D\|GRIN3A\|GRIN3B
MoA:	glutamate receptor antagonist
SMILES:	NC(=O)OCC(COC(N)=O)c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
3422	BRD-K99107520	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
3917	BRD-K99107520	VCAP	10 uM	24 h	0.2	0.84	0.0	-0.24	-0.82	0.15
24707	BRD-K99107520	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
42504	BRD-K99107520	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42813	BRD-K99107520	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
43678	BRD-K99107520	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
43978	BRD-K99107520	PHH	10 uM	24 h	0.0	0.0	0.0	0.31	1.09	0.67
44226	BRD-K99107520	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121782	BRD-K99107520	HT29	3.33 uM	24 h	0.0	0.0	0.0	0.28	0.98	0.36
121833	BRD-K99107520	PC3	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121863	BRD-K99107520	YAPC	0.37 uM	24 h	-0.3	-1.23	0.64	-0.41	-1.37	2.02
129746	BRD-K99107520	A375	0.01 uM	24 h	0.0	0.0	0.0	0.36	1.26	1.29
129779	BRD-K99107520	HA1E	0.08 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.37
129810	BRD-K99107520	HEK293	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129864	BRD-K99107520	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129908	BRD-K99107520	JURKAT	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129936	BRD-K99107520	MCF10A	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129987	BRD-K99107520	MCF??7.00	0.01 uM	24 h	0.0	0.0	0.0	0.27	0.96	0.34
130021	BRD-K99107520	MDAMB231	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130094	BRD-K99107520	THP1	0.08 uM	24 h	0.0	0.0	0.0	0.22	0.77	0.06

Summary