CMap Candidate Details
Structure:
| CMap ID: | C02115 |
| Pert ID: | BRD-K12513978 |
| Compound Name: | fenbufen |
| Targets: | PTGS1|PTGS2 |
| MoA: | cyclooxygenase inhibitor |
| SMILES: | OC(=O)CCC(=O)c1ccc(cc1)-c1ccccc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 5185 | BRD-K12513978 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5301 | BRD-K12513978 | HA1E | 10 uM | 24 h | -0.27 | -1.12 | 0.38 | 0.0 | 0.0 | 0.0 |
| 5579 | BRD-K12513978 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.23 | 0.82 | 0.1 |
| 5883 | BRD-K12513978 | HEPG2 | 10 uM | 6 h | -0.27 | -1.13 | 0.41 | 0.0 | 0.0 | 0.0 |
| 6261 | BRD-K12513978 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.02 | 0.62 |
| 6343 | BRD-K12513978 | VCAP | 10 uM | 24 h | -0.19 | -0.77 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39428 | BRD-K12513978 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39631 | BRD-K12513978 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40229 | BRD-K12513978 | HT29 | 10 uM | 6 h | -0.22 | -0.9 | 0.04 | -0.27 | -0.91 | 0.31 |
| 40754 | BRD-K12513978 | NEU | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 41054 | BRD-K12513978 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 41383 | BRD-K12513978 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51347 | BRD-K12513978 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.21 | 1.24 |
| 91317 | BRD-K12513978 | HUH7 | 12.5 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |