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CMap Candidate Details

Structure:
CMap ID: C00212
Pert ID: BRD-K33396764
Compound Name: alpha-linolenic-acid
Targets: ELOVL4|FADS1|FADS2|FFAR1|FFAR4|PTGS2|SLC8A1|TRPV1
MoA: omega 3 fatty acid stimulant
SMILES: CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4216 BRD-K33396764 HA1E 10 uM 6 h 0.23 0.97 0.08 0.28 1.01 0.44
4564 BRD-K33396764 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4799 BRD-K33396764 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5075 BRD-K33396764 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39121 BRD-K33396764 A375 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.06 0.73
39444 BRD-K33396764 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39673 BRD-K33396764 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40261 BRD-K33396764 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40462 BRD-K33396764 MCF??7.00 10 uM 24 h -0.24 -1.0 0.15 0.0 0.0 0.0
40792 BRD-K33396764 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41094 BRD-K33396764 NPC 10 uM 24 h 0.17 0.73 0.0 0.0 0.0 0.0
41427 BRD-K33396764 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53443 BRD-K33396764 HEPG2 0.25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53506 BRD-K33396764 HUH7 1.11 uM 24 h 0.0 0.0 0.0 0.33 1.18 0.98
53723 BRD-K33396764 PHH 1.11 uM 6 h 0.0 0.0 0.0 0.21 0.73 0.03
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).