Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C02121
Pert ID: BRD-K50388907
Compound Name: fenofibrate
Targets: MMP25|PPARA
MoA: PPAR receptor agonist
SMILES: CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3036 BRD-K50388907 HA1E 10 uM 6 h 0.24 0.99 0.1 0.26 0.91 0.24
3374 BRD-K50388907 HCC515 10 uM 6 h -0.23 -0.97 0.11 0.31 1.11 0.72
3520 BRD-K50388907 PC3 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
3820 BRD-K50388907 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44414 BRD-K50388907 A375 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.56
44596 BRD-K50388907 A549 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
44980 BRD-K50388907 ASC 10 uM 24 h 0.18 0.77 0.0 0.0 0.0 0.0
45276 BRD-K50388907 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45544 BRD-K50388907 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46096 BRD-K50388907 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46412 BRD-K50388907 PHH 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
46735 BRD-K50388907 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51225 BRD-K50388907 MCF??7.00 10 uM 24 h 0.31 1.28 0.64 0.0 0.0 0.0
91323 BRD-K50388907 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).