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CMap Candidate Details

Structure:
CMap ID: C02123
Pert ID: BRD-A50684349
Compound Name: fenoldopam
Targets: ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|DRD1|DRD4|DRD5
MoA: dopamine receptor agonist
SMILES: Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3318 BRD-A50684349 HCC515 10 uM 6 h 0.0 0.0 0.0 0.18 0.63 0.0
24643 BRD-A50684349 A549 10 uM 6 h 0.31 1.3 0.69 0.0 0.0 0.0
25476 BRD-A50684349 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44771 BRD-A50684349 ASC 10 uM 24 h 0.27 1.12 0.26 0.26 0.92 0.26
45091 BRD-A50684349 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45890 BRD-A50684349 NPC 10 uM 24 h 0.24 1.02 0.12 -0.4 -1.34 1.85
46206 BRD-A50684349 PHH 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
46521 BRD-A50684349 SKB 10 uM 24 h -0.3 -1.25 0.68 -0.26 -0.89 0.26
91319 BRD-A50684349 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
100200 BRD-A50684349 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121719 BRD-A50684349 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121759 BRD-A50684349 HELA 10 uM 24 h -0.19 -0.78 0.0 0.0 0.0 0.0
121792 BRD-A50684349 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129788 BRD-A50684349 HA1E 0.25 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
129822 BRD-A50684349 HEK293 0.01 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
129949 BRD-A50684349 MCF10A 0.01 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
129996 BRD-A50684349 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130033 BRD-A50684349 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.39 1.37 2.12
130080 BRD-A50684349 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130105 BRD-A50684349 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130153 BRD-A50684349 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).