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CMap Candidate Details

Structure:
CMap ID: C02128
Pert ID: BRD-K89085489
Compound Name: fenretinide
Targets: RARA
MoA: apoptosis stimulant; retinoid receptor agonist
SMILES: CC(/C=C/C1=C(C)CCCC1(C)C)=C\C=C\C(C)=C\C(=O)Nc1ccc(O)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33944 BRD-K89085489 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34208 BRD-K89085489 ASC 10 uM 24 h 0.19 0.79 0.0 -0.36 -1.2 1.2
34713 BRD-K89085489 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35863 BRD-K89085489 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36010 BRD-K89085489 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36379 BRD-K89085489 PHH 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.36
36680 BRD-K89085489 SKB 10 uM 24 h 0.2 0.83 0.0 -0.43 -1.46 15.35
36892 BRD-K89085489 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90932 BRD-K89085489 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
97571 BRD-K89085489 NKDBA 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.45 15.35
98949 BRD-K89085489 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116279 BRD-K89085489 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
116365 BRD-K89085489 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.05
116460 BRD-K89085489 HEPG2 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.36 2.02
116511 BRD-K89085489 HT29 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
116559 BRD-K89085489 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).