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CMap Candidate Details

Structure:
CMap ID: C02142
Pert ID: BRD-K61951118
Compound Name: FG-7142
Targets:
MoA: GABA benzodiazepine site receptor inverse agonist
SMILES: CNC(=O)c1cc2c(cn1)[nH]c1ccccc21
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6792 BRD-K61951118 A375 10 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
7021 BRD-K61951118 A549 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.36
7349 BRD-K61951118 HA1E 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
7702 BRD-K61951118 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.14
7904 BRD-K61951118 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8135 BRD-K61951118 MCF??7.00 10 uM 6 h -0.22 -0.9 0.04 -0.39 -1.31 1.71
8402 BRD-K61951118 PC3 10 uM 24 h 0.0 0.0 0.0 0.39 1.39 2.17
8716 BRD-K61951118 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99297 BRD-K61951118 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).