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CMap Candidate Details

Structure:
CMap ID: C02147
Pert ID: BRD-K07160047
Compound Name: fiacitabine
Targets:
MoA: DNA synthesis inhibitor
SMILES: Nc1nc(=O)n(cc1I)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122729 BRD-K07160047 MCF10A 1.11 uM 24 h 0.23 0.95 0.07 0.0 0.0 0.0
130870 BRD-K07160047 A375 0.03 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.8
130888 BRD-K07160047 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130919 BRD-K07160047 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130939 BRD-K07160047 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130972 BRD-K07160047 HELA 0.01 uM 24 h 0.21 0.9 0.02 0.0 0.0 0.0
131003 BRD-K07160047 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131051 BRD-K07160047 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131087 BRD-K07160047 MCF??7.00 0.01 uM 24 h 0.23 0.95 0.06 -0.45 -1.51 15.35
131124 BRD-K07160047 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131154 BRD-K07160047 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131190 BRD-K07160047 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).