CMap Candidate Details
Structure:
| CMap ID: | C02149 |
| Pert ID: | BRD-K57371763 |
| Compound Name: | fidaxomicin |
| Targets: | |
| MoA: | RNA polymerase inhibitor |
| SMILES: | CC[C@H]1\C=C(C)/[C@@H](O)C\C=C\C=C(CO[C@@H]2O[C@H](C)[C@@H](OC(=O)c3c(O)c(Cl)c(O)c(Cl)c3CC)[C@H](O)[C@@H]2OC)\C(=O)O[C@H](C\C=C(C)\C=C(C)[C@H]1O[C@@H]1OC(C)(C)[C@@H](OC(=O)C(C)C)[C@H](O)[C@H]1O)[C@@H](C)O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123515 | BRD-K57371763 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123534 | BRD-K57371763 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.37 | -1.23 | 1.25 |
| 123562 | BRD-K57371763 | HEK293 | 0.125 uM | 24 h | 0.27 | 1.14 | 0.3 | 0.22 | 0.79 | 0.07 |
| 123613 | BRD-K57371763 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.23 | 1.25 |
| 123640 | BRD-K57371763 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123679 | BRD-K57371763 | MCF10A | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123722 | BRD-K57371763 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123741 | BRD-K57371763 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.27 | 1.39 |
| 132133 | BRD-K57371763 | YAPC | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.42 | -1.4 | 2.02 |