CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02155
Pert ID:	BRD-K88025533
Compound Name:	fingolimod
Targets:	S1PR1\|S1PR5
MoA:	immunosuppressant; sphingosine phosphate receptor agonist
SMILES:	CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95543	BRD-K88025533	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
95679	BRD-K88025533	U2OS	10 uM	48 h	0.0	0.0	0.0	0.0	0.0	0.0
118374	BRD-K88025533	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
118485	BRD-K88025533	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
118531	BRD-K88025533	HEPG2	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121746	BRD-K88025533	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121777	BRD-K88025533	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121810	BRD-K88025533	HT29	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121826	BRD-K88025533	MCF??7.00	10 uM	24 h	-0.23	-0.96	0.1	-0.38	-1.28	1.45
121854	BRD-K88025533	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121877	BRD-K88025533	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129852	BRD-K88025533	HEK293	0.03 uM	24 h	0.14	0.6	0.0	0.0	0.0	0.0
129929	BRD-K88025533	JURKAT	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129977	BRD-K88025533	MCF10A	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130063	BRD-K88025533	MDAMB231	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130134	BRD-K88025533	THP1	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary