Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C02158
Pert ID: BRD-A50675702
Compound Name: fipronil
Targets:
MoA: chloride channel blocker; GABA gated chloride channel blocker
SMILES: Nc1c(c(nn1-c1c(Cl)cc(cc1Cl)C(F)(F)F)C#N)S(=O)C(F)(F)F
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5525 BRD-A50675702 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6469 BRD-A50675702 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37513 BRD-A50675702 ASC 10 uM 24 h 0.31 1.29 0.65 -0.33 -1.1 0.86
37828 BRD-A50675702 HEPG2 10 uM 6 h -0.26 -1.07 0.28 -0.4 -1.34 1.85
38155 BRD-A50675702 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
38362 BRD-A50675702 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38645 BRD-A50675702 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38868 BRD-A50675702 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100199 BRD-A50675702 U2OS 12 uM 6 h 0.25 1.03 0.13 -0.23 -0.79 0.1
125249 BRD-A50675702 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125267 BRD-A50675702 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125287 BRD-A50675702 HA1E 0.125 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
125338 BRD-A50675702 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125360 BRD-A50675702 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125533 BRD-A50675702 THP1 3.33 uM 24 h -0.24 -1.02 0.18 0.22 0.77 0.06
133467 BRD-A50675702 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133497 BRD-A50675702 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133531 BRD-A50675702 MCF10A 0.03 uM 24 h -0.23 -0.94 0.08 -0.3 -1.0 0.53
133572 BRD-A50675702 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133591 BRD-A50675702 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133649 BRD-A50675702 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.39
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).