CMap Candidate Details
Structure:
| CMap ID: | C02159 |
| Pert ID: | BRD-K17513304 |
| Compound Name: | firategrast |
| Targets: | ITGA4 |
| MoA: | integrin antagonist |
| SMILES: | CCOCc1cc(OC)c(-c2ccc(C[C@H](NC(=O)c3c(F)cccc3F)C(O)=O)cc2)c(OC)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95551 | BRD-K17513304 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.72 | 0.04 |
| 95561 | BRD-K17513304 | MCF??7.00 | 0.12 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95719 | BRD-K17513304 | U2OS | 10 uM | 6 h | 0.27 | 1.11 | 0.25 | 0.0 | 0.0 | 0.0 |
| 96665 | BRD-K17513304 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 97314 | BRD-K17513304 | HAP1 | 0.66 uM | 24 h | -0.32 | -1.33 | 0.92 | -0.24 | -0.8 | 0.12 |
| 97336 | BRD-K17513304 | A375 | 0.66 uM | 24 h | 0.17 | 0.69 | 0.0 | -0.23 | -0.77 | 0.08 |
| 120364 | BRD-K17513304 | HELA | 0.37 uM | 3 h | -0.22 | -0.91 | 0.05 | 0.3 | 1.07 | 0.63 |
| 120489 | BRD-K17513304 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128908 | BRD-K17513304 | HA1E | 0.01 uM | 24 h | 0.23 | 0.97 | 0.08 | 0.29 | 1.02 | 0.49 |
| 128953 | BRD-K17513304 | HT29 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.98 | 0.47 |