CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02169
Pert ID:	BRD-K47639036
Compound Name:	flavoxate
Targets:	CHRM1\|CHRM2
MoA:	acetylcholine receptor antagonist
SMILES:	Cc1c(oc2c(cccc2c1=O)C(=O)OCCN1CCCCC1)-c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
3215	BRD-K47639036	HCC515	10 uM	24 h	0.0	0.0	0.0	-0.29	-0.98	0.48
3814	BRD-K47639036	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42372	BRD-K47639036	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
42693	BRD-K47639036	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.21	-0.71	0.03
43860	BRD-K47639036	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125313	BRD-K47639036	HEK293	0.125 uM	24 h	-0.25	-1.04	0.21	-0.3	-1.01	0.57
125445	BRD-K47639036	MCF??7.00	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125473	BRD-K47639036	MDAMB231	0.37 uM	24 h	-0.27	-1.14	0.42	-0.36	-1.2	1.21
125517	BRD-K47639036	THP1	0.37 uM	24 h	-0.23	-0.96	0.1	-0.28	-0.94	0.38
125546	BRD-K47639036	YAPC	0.37 uM	24 h	0.21	0.88	0.02	-0.38	-1.28	1.45
133339	BRD-K47639036	A375	0.74 uM	24 h	-0.19	-0.8	0.0	0.0	0.0	0.0
133364	BRD-K47639036	A549	0.74 uM	24 h	0.23	0.96	0.08	0.0	0.0	0.0
133389	BRD-K47639036	HA1E	0.74 uM	24 h	-0.24	-1.02	0.18	-0.31	-1.05	0.7
133422	BRD-K47639036	HELA	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133455	BRD-K47639036	HT29	0.74 uM	24 h	0.0	0.0	0.0	-0.38	-1.27	1.4
133484	BRD-K47639036	JURKAT	2.22 uM	24 h	0.28	1.18	0.39	0.0	0.0	0.0
133518	BRD-K47639036	MCF10A	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133582	BRD-K47639036	PC3	0.08 uM	24 h	0.27	1.13	0.3	0.0	0.0	0.0

Summary