CMap Candidate Details
Structure:
| CMap ID: | C02184 |
| Pert ID: | BRD-K66788707 |
| Compound Name: | fludarabine |
| Targets: | ADA|RRM1|RRM2 |
| MoA: | ribonucleotide reductase inhibitor |
| SMILES: | Nc1nc(F)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1202 | BRD-K66788707 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 1248 | BRD-K66788707 | A549 | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | -0.18 | -0.6 | 0.0 |
| 1290 | BRD-K66788707 | MCF??7.00 | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.25 | 0.89 | 0.2 |
| 1353 | BRD-K66788707 | U2OS | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.73 | 0.05 |
| 49876 | BRD-K66788707 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50221 | BRD-K66788707 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50394 | BRD-K66788707 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50570 | BRD-K66788707 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51168 | BRD-K66788707 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |