CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02187
Pert ID:	BRD-A49765801
Compound Name:	fludroxycortide
Targets:	NR3C1\|SERPINA6
MoA:	glucocorticoid receptor agonist
SMILES:	CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)CC[C@]5(C)C4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4310	BRD-A49765801	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
4999	BRD-A49765801	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37512	BRD-A49765801	ASC	10 uM	24 h	-0.2	-0.85	0.01	0.0	0.0	0.0
38361	BRD-A49765801	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125333	BRD-A49765801	HEK293	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125382	BRD-A49765801	HT29	0.04 uM	24 h	-0.24	-1.0	0.14	0.0	0.0	0.0
125422	BRD-A49765801	MCF10A	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.88	0.24
125460	BRD-A49765801	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125477	BRD-A49765801	MDAMB231	10 uM	24 h	0.0	0.0	0.0	-0.27	-0.91	0.31
133349	BRD-A49765801	A375	2.22 uM	24 h	-0.21	-0.88	0.03	0.29	1.01	0.46
133372	BRD-A49765801	A549	2.22 uM	24 h	-0.24	-1.0	0.14	-0.27	-0.92	0.31
133401	BRD-A49765801	HA1E	2.22 uM	24 h	0.0	0.0	0.0	-0.4	-1.34	1.85
133436	BRD-A49765801	HELA	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133492	BRD-A49765801	JURKAT	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133590	BRD-A49765801	PC3	0.25 uM	24 h	-0.31	-1.31	0.82	-0.29	-0.97	0.46
133613	BRD-A49765801	THP1	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133644	BRD-A49765801	YAPC	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary