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CMap Candidate Details

Structure:
CMap ID: C02193
Pert ID: BRD-K61496577
Compound Name: flumethasone
Targets: NR3C1|PLA2G1B
MoA: glucocorticoid receptor agonist
SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4127 BRD-K61496577 HA1E 10 uM 24 h 0.28 1.19 0.41 0.0 0.0 0.0
4583 BRD-K61496577 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.24 1.31
4813 BRD-K61496577 PC3 10 uM 6 h 0.25 1.03 0.13 0.23 0.82 0.1
4945 BRD-K61496577 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39153 BRD-K61496577 A375 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
39334 BRD-K61496577 A549 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.35
39726 BRD-K61496577 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40024 BRD-K61496577 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.23 0.81 0.09
40298 BRD-K61496577 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40490 BRD-K61496577 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
41144 BRD-K61496577 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41482 BRD-K61496577 SKB 10 uM 24 h -0.25 -1.03 0.2 -0.15 -0.51 0.0
99293 BRD-K61496577 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).