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CMap Candidate Details

Structure:
CMap ID: C02196
Pert ID: BRD-K29582677
Compound Name: flunarizine
Targets: CACNA1G|CACNA1H|CACNA1I|CALM1|HRH1
MoA: calcium channel blocker
SMILES: Fc1ccc(cc1)C(N1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1415 BRD-K29582677 NPC 25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5197 BRD-K29582677 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5442 BRD-K29582677 HA1E 10 uM 6 h -0.32 -1.33 0.9 0.0 0.0 0.0
5604 BRD-K29582677 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6086 BRD-K29582677 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6176 BRD-K29582677 PC3 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.91
6331 BRD-K29582677 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39314 BRD-K29582677 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39662 BRD-K29582677 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39976 BRD-K29582677 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40252 BRD-K29582677 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40782 BRD-K29582677 NEU 10 uM 24 h 0.19 0.78 0.0 -0.31 -1.05 0.69
41416 BRD-K29582677 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91042 BRD-K29582677 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).