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CMap Candidate Details

Structure:
CMap ID: C02202
Pert ID: BRD-A13133631
Compound Name: fluorometholone
Targets: NR3C1
MoA: glucocorticoid receptor agonist
SMILES: C[C@H]1CC2C3CC[C@](O)(C(C)=O)[C@@]3(C)C[C@H](O)[C@]2(F)C2(C)C=CC(=O)C=C12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7055 BRD-A13133631 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7207 BRD-A13133631 HA1E 10 uM 24 h -0.17 -0.71 0.0 0.0 0.0 0.0
7508 BRD-A13133631 HCC515 10 uM 6 h -0.25 -1.06 0.25 -0.42 -1.4 2.02
8745 BRD-A13133631 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
122247 BRD-A13133631 A375 10 uM 24 h 0.19 0.78 0.0 0.0 0.0 0.0
122329 BRD-A13133631 HELA 0.125 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
122357 BRD-A13133631 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122387 BRD-A13133631 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122415 BRD-A13133631 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122470 BRD-A13133631 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130622 BRD-A13133631 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130703 BRD-A13133631 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
130810 BRD-A13133631 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.12
130833 BRD-A13133631 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).