CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02205
Pert ID:	BRD-A31159102
Compound Name:	fluoxetine
Targets:	ANO1\|HTR2B\|SLC6A4
MoA:	selective serotonin reuptake inhibitor (SSRI)
SMILES:	CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1466	BRD-A31159102	NPC	25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7521	BRD-A31159102	HCC515	10 uM	6 h	0.0	0.0	0.0	0.35	1.24	1.24
20192	BRD-A31159102	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
21680	BRD-A31159102	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
91337	BRD-A31159102	HUH7	10 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
95476	BRD-A31159102	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
98289	BRD-A31159102	NEU	10 uM	24 h	0.0	0.0	0.0	0.25	0.89	0.21
120508	BRD-A31159102	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120540	BRD-A31159102	A549	10 uM	24 h	0.3	1.24	0.51	0.38	1.34	1.72
120586	BRD-A31159102	HA1E	10 uM	24 h	0.24	0.99	0.1	0.4	1.43	2.2
120612	BRD-A31159102	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120641	BRD-A31159102	HT29	10 uM	24 h	-0.19	-0.78	0.0	0.0	0.0	0.0
120691	BRD-A31159102	JURKAT	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120745	BRD-A31159102	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.36
120765	BRD-A31159102	PC3	10 uM	24 h	0.0	0.0	0.0	0.21	0.74	0.03
120797	BRD-A31159102	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary