CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02207
Pert ID:	BRD-K70487031
Compound Name:	flupentixol
Targets:	ADRA1A\|CHRM1\|DRD1\|DRD2\|DRD3\|DRD5\|HTR2A
MoA:	dopamine receptor antagonist
SMILES:	OCCN1CCN(CC\C=C2\c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4135	BRD-K70487031	HA1E	10 uM	24 h	0.0	0.0	0.0	0.37	1.31	1.59
4472	BRD-K70487031	HCC515	10 uM	24 h	0.0	0.0	0.0	0.29	1.01	0.45
4713	BRD-K70487031	PC3	10 uM	24 h	0.19	0.78	0.0	0.31	1.1	0.69
5117	BRD-K70487031	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.37	-1.25	1.35
39167	BRD-K70487031	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
39480	BRD-K70487031	A549	10 uM	6 h	-0.28	-1.16	0.47	0.31	1.1	0.68
39752	BRD-K70487031	ASC	10 uM	24 h	-0.25	-1.04	0.21	-0.37	-1.26	1.35
40045	BRD-K70487031	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40312	BRD-K70487031	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40498	BRD-K70487031	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.18	1.14
40854	BRD-K70487031	NEU	10 uM	24 h	0.21	0.88	0.01	0.25	0.88	0.18
41169	BRD-K70487031	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41507	BRD-K70487031	SKB	10 uM	24 h	0.17	0.73	0.0	0.3	1.07	0.62

Summary