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CMap Candidate Details

Structure:
CMap ID: C02221
Pert ID: BRD-A00218260
Compound Name: flutrimazole
Targets:
MoA: sterol demethylase inhibitor
SMILES: Fc1ccc(cc1)C(c1ccccc1)(c1ccccc1F)n1ccnc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122852 BRD-A00218260 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122875 BRD-A00218260 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122928 BRD-A00218260 HELA 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
122959 BRD-A00218260 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123000 BRD-A00218260 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123070 BRD-A00218260 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
123089 BRD-A00218260 MDAMB231 1.11 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
123141 BRD-A00218260 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123161 BRD-A00218260 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123211 BRD-A00218260 YAPC 3.33 uM 24 h 0.2 0.83 0.0 0.0 0.0 0.0
131198 BRD-A00218260 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131227 BRD-A00218260 A549 0.74 uM 24 h -0.19 -0.77 0.0 0.0 0.0 0.0
131337 BRD-A00218260 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131389 BRD-A00218260 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.36 1.29 1.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).