CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02223
Pert ID:	BRD-K53517854
Compound Name:	fluvoxamine
Targets:	SLC6A4
MoA:	selective serotonin reuptake inhibitor (SSRI)
SMILES:	COCCCC\C(c1ccc(cc1)C(F)(F)F)=N/OCCN
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95320	BRD-K53517854	A549	10 uM	48 h	0.0	0.0	0.0	-0.27	-0.91	0.31
95403	BRD-K53517854	U2OS	10 uM	24 h	0.0	0.0	0.0	0.35	1.23	1.19
124299	BRD-K53517854	HA1E	10 uM	24 h	-0.32	-1.34	0.98	0.0	0.0	0.0
124352	BRD-K53517854	HELA	1.11 uM	24 h	0.25	1.05	0.18	0.31	1.09	0.68
124384	BRD-K53517854	HT29	3.33 uM	24 h	0.19	0.79	0.0	0.0	0.0	0.0
124417	BRD-K53517854	JURKAT	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124449	BRD-K53517854	MCF10A	0.37 uM	24 h	0.0	0.0	0.0	0.28	0.98	0.37
124487	BRD-K53517854	MDAMB231	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124518	BRD-K53517854	PC3	0.125 uM	24 h	0.27	1.12	0.26	0.0	0.0	0.0
132331	BRD-K53517854	A375	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132423	BRD-K53517854	HEK293	0.03 uM	24 h	0.0	0.0	0.0	-0.27	-0.91	0.3
132522	BRD-K53517854	MCF??7.00	0.25 uM	24 h	0.0	0.0	0.0	0.24	0.86	0.16
132605	BRD-K53517854	THP1	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132642	BRD-K53517854	YAPC	0.74 uM	24 h	0.0	0.0	0.0	-0.32	-1.08	0.81

Summary