CMap Candidate Details
Structure:
| CMap ID: | C02225 |
| Pert ID: | BRD-K18673820 |
| Compound Name: | folic-acid |
| Targets: | FOLR2|FOLR3|SLC19A1|SLC46A1 |
| MoA: | folate receptor ligand |
| SMILES: | Nc1nc(=O)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2[nH]1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120256 | BRD-K18673820 | A375 | 3.33 uM | 24 h | -0.24 | -0.99 | 0.14 | 0.0 | 0.0 | 0.0 |
| 120297 | BRD-K18673820 | A549 | 10 uM | 24 h | -0.24 | -0.99 | 0.13 | 0.24 | 0.84 | 0.13 |
| 120367 | BRD-K18673820 | HELA | 0.04 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120423 | BRD-K18673820 | MCF??7.00 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120502 | BRD-K18673820 | YAPC | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128915 | BRD-K18673820 | HA1E | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.96 |
| 128963 | BRD-K18673820 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128982 | BRD-K18673820 | PC3 | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |