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CMap Candidate Details

Structure:
CMap ID: C02227
Pert ID: BRD-K44942188
Compound Name: fomocaine
Targets:
MoA: voltage-gated sodium channel modulator
SMILES: C(CN1CCOCC1)Cc1ccc(COc2ccccc2)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125230 BRD-K44942188 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125292 BRD-K44942188 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.33 1.18 1.0
125345 BRD-K44942188 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125367 BRD-K44942188 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125412 BRD-K44942188 MCF10A 10 uM 24 h -0.27 -1.14 0.42 -0.42 -1.42 3.55
125428 BRD-K44942188 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125539 BRD-K44942188 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133353 BRD-K44942188 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133380 BRD-K44942188 HA1E 0.74 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
133472 BRD-K44942188 JURKAT 0.03 uM 24 h 0.3 1.25 0.56 -0.36 -1.2 1.21
133537 BRD-K44942188 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133576 BRD-K44942188 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133593 BRD-K44942188 THP1 2.22 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).