CMap Candidate Details
Structure:
| CMap ID: | C02229 |
| Pert ID: | BRD-A26503646 |
| Compound Name: | formestane |
| Targets: | CYP19A1 |
| MoA: | aromatase inhibitor |
| SMILES: | C[C@]12CC[C@H]3[C@@H](CCC4C(=O)C(=O)CC[C@]34C)[C@@H]1CCC2=O |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 91364 | BRD-A26503646 | HUH7 | 12 uM | 72 h | 0.23 | 0.96 | 0.07 | 0.32 | 1.14 | 0.87 |
| 95354 | BRD-A26503646 | MCF??7.00 | 0.12 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95409 | BRD-A26503646 | U2OS | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96385 | BRD-A26503646 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.78 | 0.1 |
| 120877 | BRD-A26503646 | A375 | 3.33 uM | 24 h | -0.23 | -0.95 | 0.09 | -0.28 | -0.95 | 0.41 |
| 120895 | BRD-A26503646 | A549 | 3.33 uM | 24 h | 0.29 | 1.19 | 0.42 | -0.26 | -0.89 | 0.26 |
| 120976 | BRD-A26503646 | HEK293 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121133 | BRD-A26503646 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129144 | BRD-A26503646 | HA1E | 2.22 uM | 24 h | 0.18 | 0.76 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129174 | BRD-A26503646 | HELA | 0.08 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129206 | BRD-A26503646 | HT29 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.97 | 0.45 |