CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00223
Pert ID:	BRD-K00610438
Compound Name:	altanserin
Targets:	HTR2A
MoA:	serotonin receptor antagonist
SMILES:	Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=S)[nH]c3ccccc3c2=O)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4330	BRD-K00610438	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
25315	BRD-K00610438	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44807	BRD-K00610438	ASC	10 uM	24 h	-0.3	-1.24	0.67	-0.34	-1.16	1.1
45123	BRD-K00610438	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45925	BRD-K00610438	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46244	BRD-K00610438	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46558	BRD-K00610438	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122829	BRD-K00610438	A375	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122879	BRD-K00610438	HEK293	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122931	BRD-K00610438	HELA	0.125 uM	24 h	0.0	0.0	0.0	0.32	1.15	0.88
122963	BRD-K00610438	HT29	10 uM	24 h	0.21	0.87	0.01	0.0	0.0	0.0
123004	BRD-K00610438	JURKAT	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123093	BRD-K00610438	MDAMB231	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123165	BRD-K00610438	THP1	3.33 uM	24 h	-0.23	-0.98	0.12	-0.27	-0.91	0.31
131230	BRD-K00610438	A549	0.03 uM	24 h	0.0	0.0	0.0	0.28	0.99	0.39
131270	BRD-K00610438	HA1E	0.03 uM	24 h	0.0	0.0	0.0	-0.22	-0.73	0.05
131341	BRD-K00610438	HUVEC	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131391	BRD-K00610438	MCF10A	0.01 uM	24 h	0.0	0.0	0.0	-0.24	-0.8	0.12
131425	BRD-K00610438	MCF??7.00	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131454	BRD-K00610438	PC3	2.22 uM	24 h	-0.23	-0.98	0.12	0.0	0.0	0.0
131484	BRD-K00610438	YAPC	2.22 uM	24 h	0.31	1.28	0.63	-0.27	-0.9	0.29

Summary