CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02234
Pert ID:	BRD-K09602097
Compound Name:	forskolin
Targets:	ADCY2\|ADCY5\|GNAS
MoA:	adenylyl cyclase activator
SMILES:	CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5299	BRD-K09602097	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.32	-1.08	0.79
5756	BRD-K09602097	HCC515	10 uM	6 h	-0.2	-0.83	0.0	0.0	0.0	0.0
6403	BRD-K09602097	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44670	BRD-K09602097	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44849	BRD-K09602097	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45158	BRD-K09602097	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45964	BRD-K09602097	NPC	10 uM	24 h	0.23	0.96	0.07	0.33	1.16	0.9
46284	BRD-K09602097	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46600	BRD-K09602097	SKB	10 uM	24 h	-0.22	-0.92	0.06	0.0	0.0	0.0
97696	BRD-K09602097	NKDBA	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121156	BRD-K09602097	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121281	BRD-K09602097	HT29	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.03	0.64
121351	BRD-K09602097	YAPC	10 uM	24 h	0.25	1.05	0.17	0.21	0.74	0.03
129265	BRD-K09602097	HELA	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129339	BRD-K09602097	MCF??7.00	2.22 uM	24 h	0.0	0.0	0.0	0.25	0.9	0.22
129354	BRD-K09602097	PC3	2.22 uM	24 h	0.0	0.0	0.0	-0.38	-1.27	1.4

Summary