CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02253
Pert ID:	BRD-K59875992
Compound Name:	FPL-62064
Targets:
MoA:	cyclooxygenase inhibitor; lipoxygenase inhibitor
SMILES:	COc1ccc(Nc2ccn(n2)-c2ccccc2)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95548	BRD-K59875992	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
95682	BRD-K59875992	U2OS	0.12 uM	48 h	0.0	0.0	0.0	0.0	0.0	0.0
96358	BRD-K59875992	A375	3.33 uM	24 h	0.0	0.0	0.0	-0.17	-0.56	0.0
96429	BRD-K59875992	PC3	3.33 uM	24 h	-0.28	-1.16	0.46	-0.29	-0.98	0.48
123919	BRD-K59875992	HEK293	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124021	BRD-K59875992	JURKAT	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
124072	BRD-K59875992	MCF10A	1.11 uM	24 h	-0.27	-1.14	0.42	-0.28	-0.93	0.34
124139	BRD-K59875992	MDAMB231	1.11 uM	24 h	-0.22	-0.92	0.06	0.0	0.0	0.0
124202	BRD-K59875992	THP1	3.33 uM	24 h	-0.19	-0.79	0.0	0.38	1.35	1.72
124255	BRD-K59875992	YAPC	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
132176	BRD-K59875992	HA1E	2.22 uM	24 h	0.29	1.22	0.48	0.0	0.0	0.0
132207	BRD-K59875992	HELA	0.74 uM	24 h	-0.2	-0.82	0.0	0.24	0.84	0.13
132240	BRD-K59875992	HT29	2.22 uM	24 h	0.0	0.0	0.0	0.27	0.95	0.31
132264	BRD-K59875992	MCF??7.00	0.03 uM	24 h	-0.24	-1.02	0.18	0.0	0.0	0.0

Summary