CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02254
Pert ID:	BRD-K78959463
Compound Name:	FPL-64176
Targets:	CACNA1C\|CACNA1S
MoA:	calcium channel activator
SMILES:	COC(=O)c1c(C)[nH]c(C)c1C(=O)c1ccccc1Cc1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
8988	BRD-K78959463	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
9514	BRD-K78959463	AGS	10 uM	6 h	0.0	0.0	0.0	-0.39	-1.32	1.71
9819	BRD-K78959463	H1299	10 uM	6 h	0.0	0.0	0.0	-0.24	-0.79	0.11
10083	BRD-K78959463	HA1E	10 uM	6 h	0.0	0.0	0.0	-0.2	-0.67	0.01
10260	BRD-K78959463	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
12137	BRD-K78959463	NCIH596	10 uM	6 h	-0.22	-0.92	0.06	-0.29	-0.96	0.44
12441	BRD-K78959463	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
13365	BRD-K78959463	U937	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13684	BRD-K78959463	VCAP	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44623	BRD-K78959463	A549	10 uM	24 h	0.0	0.0	0.0	0.32	1.12	0.79
45036	BRD-K78959463	ASC	10 uM	24 h	0.19	0.79	0.0	0.28	0.98	0.37
45325	BRD-K78959463	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45583	BRD-K78959463	HT29	10 uM	6 h	0.0	0.0	0.0	-0.25	-0.83	0.17
45850	BRD-K78959463	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	-0.26	-0.88	0.26
46148	BRD-K78959463	NPC	10 uM	24 h	-0.26	-1.09	0.32	0.25	0.87	0.18
46789	BRD-K78959463	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary