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CMap Candidate Details

Structure:
CMap ID: C02256
Pert ID: BRD-K30990140
Compound Name: FR-122047
Targets:
MoA: cyclooxygenase inhibitor
SMILES: COc1ccc(cc1)-c1nc(sc1-c1ccc(OC)cc1)C(=O)N1CCN(C)CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4093 BRD-K30990140 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4559 BRD-K30990140 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4795 BRD-K30990140 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4917 BRD-K30990140 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39113 BRD-K30990140 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39438 BRD-K30990140 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39664 BRD-K30990140 ASC 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
39977 BRD-K30990140 HEPG2 10 uM 6 h -0.31 -1.31 0.82 0.24 0.84 0.12
40253 BRD-K30990140 HT29 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.38
40607 BRD-K30990140 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.34
40784 BRD-K30990140 NEU 10 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
41085 BRD-K30990140 NPC 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
41418 BRD-K30990140 SKB 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
99821 BRD-K30990140 U2OS 10 uM 6 h 0.0 0.0 0.0 0.22 0.77 0.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).