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CMap Candidate Details

Structure:
CMap ID: C00227
Pert ID: BRD-K14619660
Compound Name: altrenogest
Targets: PGR
MoA: progestogen hormone
SMILES: C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(O)CC=C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122262 BRD-K14619660 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122301 BRD-K14619660 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122333 BRD-K14619660 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122367 BRD-K14619660 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.58
122395 BRD-K14619660 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122422 BRD-K14619660 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
122444 BRD-K14619660 PC3 3.33 uM 24 h -0.22 -0.9 0.04 0.0 0.0 0.0
122485 BRD-K14619660 THP1 10 uM 24 h -0.25 -1.05 0.22 0.0 0.0 0.0
122521 BRD-K14619660 YAPC 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
130565 BRD-K14619660 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130632 BRD-K14619660 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130717 BRD-K14619660 HT29 0.03 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).