CMap Candidate Details
Structure:
| CMap ID: | C02272 |
| Pert ID: | BRD-K78010432 |
| Compound Name: | furosemide |
| Targets: | CA2|GPR35|SLC12A1|SLC12A2 |
| MoA: | diuretic |
| SMILES: | NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90805 | BRD-K78010432 | HPTEC | 1000 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.2 | -0.66 | 0.01 |
| 91390 | BRD-K78010432 | HUH7 | 10 uM | 72 h | 0.25 | 1.04 | 0.14 | 0.0 | 0.0 | 0.0 |
| 99503 | BRD-K78010432 | U2OS | 10 uM | 6 h | 0.18 | 0.74 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127026 | BRD-K78010432 | A375 | 3.33 uM | 24 h | -0.24 | -1.01 | 0.15 | 0.0 | 0.0 | 0.0 |
| 127109 | BRD-K78010432 | HELA | 0.125 uM | 24 h | 0.22 | 0.92 | 0.04 | 0.0 | 0.0 | 0.0 |
| 127145 | BRD-K78010432 | HT29 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127167 | BRD-K78010432 | JURKAT | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.93 | 0.35 |
| 127215 | BRD-K78010432 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.29 | -0.96 | 0.44 |
| 127249 | BRD-K78010432 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 127322 | BRD-K78010432 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135053 | BRD-K78010432 | A549 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135090 | BRD-K78010432 | HA1E | 0.74 uM | 24 h | -0.2 | -0.84 | 0.01 | 0.26 | 0.93 | 0.26 |
| 135111 | BRD-K78010432 | HEK293 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135214 | BRD-K78010432 | MCF10A | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135277 | BRD-K78010432 | MDAMB231 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 135313 | BRD-K78010432 | THP1 | 0.03 uM | 24 h | -0.21 | -0.89 | 0.03 | 0.0 | 0.0 | 0.0 |