CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C02274
Pert ID:	BRD-A06935312
Compound Name:	fusidic-acid
Targets:
MoA:	bacterial 30S ribosomal subunit inhibitor
SMILES:	C[C@@H]1[C@H](O)CC[C@@]2(C)[C@H]1CC[C@@]1(C)C2[C@H](O)C[C@@H]2[C@]1(C)C[C@H](OC(C)=O)\C2=C(/CCC=C(C)C)C(O)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
95468	BRD-A06935312	U2OS	0.12 uM	6 h	0.0	0.0	0.0	-0.33	-1.11	0.92
122603	BRD-A06935312	HA1E	0.04 uM	24 h	0.0	0.0	0.0	-0.31	-1.03	0.64
122638	BRD-A06935312	HEK293	3.33 uM	24 h	0.28	1.19	0.41	0.22	0.78	0.06
122661	BRD-A06935312	HELA	1.11 uM	24 h	0.0	0.0	0.0	-0.26	-0.88	0.24
122684	BRD-A06935312	HT29	0.04 uM	24 h	-0.29	-1.22	0.61	0.0	0.0	0.0
122728	BRD-A06935312	MCF10A	3.33 uM	24 h	0.0	0.0	0.0	-0.2	-0.66	0.01
122757	BRD-A06935312	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130869	BRD-A06935312	A375	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130887	BRD-A06935312	A549	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131050	BRD-A06935312	HUVEC	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131123	BRD-A06935312	MDAMB231	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131153	BRD-A06935312	PC3	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131189	BRD-A06935312	YAPC	0.08 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary