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CMap Candidate Details

Structure:
CMap ID: C00228
Pert ID: BRD-K67043667
Compound Name: altretamine
Targets:
MoA: DNA synthesis inhibitor
SMILES: CN(C)c1nc(nc(n1)N(C)C)N(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5668 BRD-K67043667 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5947 BRD-K67043667 HEPG2 10 uM 6 h -0.28 -1.15 0.44 0.0 0.0 0.0
6360 BRD-K67043667 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
39739 BRD-K67043667 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40846 BRD-K67043667 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41156 BRD-K67043667 NPC 10 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.45
41494 BRD-K67043667 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91320 BRD-K67043667 HUH7 15 uM 72 h 0.26 1.1 0.24 0.0 0.0 0.0
99361 BRD-K67043667 U2OS 10 uM 6 h -0.22 -0.91 0.05 0.3 1.08 0.65
124621 BRD-K67043667 HA1E 3.33 uM 24 h -0.28 -1.15 0.44 -0.25 -0.83 0.16
124666 BRD-K67043667 HELA 0.125 uM 24 h -0.22 -0.93 0.07 -0.29 -0.99 0.51
124698 BRD-K67043667 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124729 BRD-K67043667 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124804 BRD-K67043667 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124845 BRD-K67043667 PC3 10 uM 24 h 0.0 0.0 0.0 0.21 0.76 0.05
124887 BRD-K67043667 THP1 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
132667 BRD-K67043667 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132694 BRD-K67043667 A549 0.03 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
132760 BRD-K67043667 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132876 BRD-K67043667 MCF10A 0.01 uM 24 h -0.26 -1.07 0.27 0.0 0.0 0.0
132904 BRD-K67043667 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
132958 BRD-K67043667 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).