CMap Candidate Details
Structure:
| CMap ID: | C02280 |
| Pert ID: | BRD-K62737565 |
| Compound Name: | gabapentin |
| Targets: | ADORA1|CACNA1A|CACNA1B|CACNA1C|CACNA1D|CACNA1E|CACNA1F|CACNA1G|CACNA1H|CACNA1I|CACNA1S|CACNA2D1|CACNA2D2|CACNA2D3|CACNA2D4|CACNB1|CACNB2|CACNB3|CACNB4|CACNG1|CACNG2|CACNG3|CACNG4|CACNG5|CACNG6|CACNG7|CACNG8|GRIN1|GRIN2A|GRIN2B|GRIN2C|GRIN2D|GRIN3A|GRIN3B |
| MoA: | calcium channel blocker |
| SMILES: | NCC1(CC(O)=O)CCCCC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 91066 | BRD-K62737565 | HUH7 | 20 uM | 72 h | -0.24 | -1.02 | 0.18 | 0.0 | 0.0 | 0.0 |
| 124601 | BRD-K62737565 | A549 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124624 | BRD-K62737565 | HA1E | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.89 | 0.27 |
| 124704 | BRD-K62737565 | HT29 | 3.33 uM | 24 h | 0.24 | 0.99 | 0.1 | 0.32 | 1.12 | 0.78 |
| 124810 | BRD-K62737565 | MDAMB231 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 124853 | BRD-K62737565 | PC3 | 0.04 uM | 24 h | 0.27 | 1.12 | 0.26 | 0.0 | 0.0 | 0.0 |
| 124894 | BRD-K62737565 | THP1 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.39 | -1.31 | 1.71 |
| 132671 | BRD-K62737565 | A375 | 0.74 uM | 24 h | -0.27 | -1.12 | 0.38 | -0.23 | -0.78 | 0.09 |
| 132767 | BRD-K62737565 | HEK293 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132796 | BRD-K62737565 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132843 | BRD-K62737565 | JURKAT | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132881 | BRD-K62737565 | MCF10A | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 132909 | BRD-K62737565 | MCF??7.00 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.11 | 0.72 |
| 132966 | BRD-K62737565 | YAPC | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |