CMap Candidate Details
Structure:
| CMap ID: | C02284 |
| Pert ID: | BRD-K89104321 |
| Compound Name: | gaboxadol |
| Targets: | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRD|GABRR1|GABRR2|GABRR3 |
| MoA: | benzodiazepine receptor agonist |
| SMILES: | Oc1noc2CNCCc12 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 52207 | BRD-K89104321 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.2 | 1.21 |
| 121738 | BRD-K89104321 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.86 | 0.22 |
| 121799 | BRD-K89104321 | HT29 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.13 | 0.97 |
| 121846 | BRD-K89104321 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.2 | 1.13 |
| 129760 | BRD-K89104321 | A375 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129837 | BRD-K89104321 | HEK293 | 0.08 uM | 24 h | -0.21 | -0.88 | 0.03 | -0.3 | -1.02 | 0.61 |
| 129875 | BRD-K89104321 | HELA | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.23 | 1.25 |
| 129921 | BRD-K89104321 | JURKAT | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.01 |
| 129963 | BRD-K89104321 | MCF10A | 0.25 uM | 24 h | 0.24 | 1.02 | 0.13 | 0.0 | 0.0 | 0.0 |
| 130048 | BRD-K89104321 | MDAMB231 | 0.74 uM | 24 h | -0.22 | -0.91 | 0.06 | -0.27 | -0.9 | 0.28 |
| 130119 | BRD-K89104321 | THP1 | 0.03 uM | 24 h | -0.25 | -1.06 | 0.25 | -0.31 | -1.06 | 0.73 |
| 130165 | BRD-K89104321 | YAPC | 0.25 uM | 24 h | -0.25 | -1.04 | 0.21 | 0.23 | 0.82 | 0.09 |