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CMap Candidate Details

Structure:
CMap ID: C02298
Pert ID: BRD-K18059238
Compound Name: gamma-linolenic-acid
Targets: PTGS1|PTGS2
MoA: cyclooxygenase inhibitor; prostanoid receptor agonist
SMILES: CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4201 BRD-K18059238 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4554 BRD-K18059238 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4660 BRD-K18059238 PC3 10 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.59
4907 BRD-K18059238 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44328 BRD-K18059238 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44538 BRD-K18059238 A549 10 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
45187 BRD-K18059238 HEPG2 10 uM 6 h -0.25 -1.05 0.23 0.0 0.0 0.0
45455 BRD-K18059238 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45664 BRD-K18059238 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46002 BRD-K18059238 NPC 10 uM 24 h 0.24 1.01 0.12 -0.35 -1.18 1.15
46320 BRD-K18059238 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46635 BRD-K18059238 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100168 BRD-K18059238 U2OS 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).